Hierarchies

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4cb376f865777ae2627ed061acaaf813664e754ef281d428fca7fed02391f092

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morningvoid||||0

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6b973722a2fb3263c7610a43c3381958aa01a868815662b1357554b83d81d6d9

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immune-compromise||||0

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http://purl.obolibrary.org/obo/CHEBI_15650

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http://purl.obolibrary.org/obo/CHEBI_16814

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http://purl.obolibrary.org/obo/CHEBI_17234

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http://purl.obolibrary.org/obo/CHEBI_23449

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http://purl.obolibrary.org/obo/CHEBI_33023

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http://purl.obolibrary.org/obo/CHEBI_35143

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http://purl.obolibrary.org/obo/CHEBI_40304

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http://purl.obolibrary.org/obo/CHEBI_5931

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http://purl.obolibrary.org/obo/CMO_0001297

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http://purl.obolibrary.org/obo/CMO_0001298

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http://purl.obolibrary.org/obo/CMO_0001299

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http://purl.obolibrary.org/obo/GO_0006954

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http://purl.obolibrary.org/obo/GO_0006955

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http://purl.obolibrary.org/obo/GO_0035710

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http://purl.obolibrary.org/obo/GO_0035711

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http://purl.obolibrary.org/obo/GO_0035712

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http://purl.obolibrary.org/obo/NCIT_C121977

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A family of proteins that are essential for the presentation of peptide antigens on cell surfaces that modulate the host defensive activities of T-cells. This protein family includes major histocompatibility complex (MHC) class I and class II proteins. [Definition Source: NCI]

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http://purl.obolibrary.org/obo/NCIT_C14139

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immune-compromise||||1

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http://purl.obolibrary.org/obo/NCIT_C19053

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T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in biosynthesis of lymphokines, cell proliferation, cell differentiation, and maturation to support immune activity. (Source: NCI Thesaurus)

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http://purl.obolibrary.org/obo/NCIT_C19255

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A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation. (Source: NCI Thesaurus)

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http://purl.obolibrary.org/obo/NCIT_C20130

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Collection of proteins that are evolutionarily related. This is reflected in the structural and functional similarities as well as in the extent of sequence conservation or residue identity. (from SCOP)